• <output id="rvd5t"><small id="rvd5t"></small></output>

        <tr id="rvd5t"></tr>

          1. <th id="rvd5t"><sup id="rvd5t"></sup></th>
            免費咨詢電話: 400-699-0631      點擊這里給我發消息

            Spermine 精胺
             產品貨號: SS3256
             產品名稱: Spermine 精胺
             產品價格/規格: 1g 300元
             產品說明書: 暫無
             更新時間: 2022-06-07
            詳細信息   訪問次數:

            • 產品介紹
            • 發表文章
            • 相關產品
            • 質檢證書
            • Spermine 精胺

              N,N′-雙(3-氨基丙基)-1,4-丁二胺 精素 肌胺 肝胺

              • 線性分子式 NH2(CH2)3NH(CH2)4NH(CH2)3NH2

              • 分子量 202.34

              • 純度:>98%

              Biochem/physiol Actions

              Spermine together with putrescine and spermidine compose a family of polyamines (polycations) that are required for the growth and survival of the vast majority of living cells. Polyamines interact with negatively charged molecules such as proteoglycans, glycated proteins and nucleic acids (DNA and RNA). Biogenic polyamines are found to modulate protein synthesis at different levels. This effect may be explained by the ability of polyamines to bind and influence the secondary structure of tRNA, mRNA, and rRNA. Spermine also helps stabilize nucleic acid helical structure and the conformation of glycated proteins such as the histones. Spermine and spermidine are components of various nucleic acid transfection protocols.
              Mixed NMDA glutamate receptor agonist/antagonist at the polyamine site. Neuroprotective effects have been observed at high concentrations (1 mM), while neurotoxicity is observed at lower concentrations. It enhances agonist effectiveness at the strychnine-insensitive glycine site. Plays a role in cellular proliferation and differentiation; inhibits neuronal nitric oxide synthase (nNOS).

              多胺位點混合型 NMDA 谷氨酸受體激動劑/拮抗劑。在高濃度 (1mM) 下觀察到神經保護作用,而在低濃度下則觀察到神經毒性。它在番木鱉堿-不敏感性甘氨酸位點能夠增強激動劑效應。在細胞增殖和分化中發揮作用;抑制神經元一氧化氮合成酶 (nNOS)。

              1g  300元  Cat:SS3256




            中科瑞泰(北京)生物科技有限公司 版權所有 京ICP備12052607 網站管理   快遞查詢   IF查詢
            電話:010-58437227 免費電話:400-699-0631 傳真:010-57909566
            點擊這里給我發消息   內勤訂貨QQ:2446698252   技術支持QQ:460449375 電子郵箱:real-times@vip.163.com